Ouvrages et articles

Principaux ouvrages

  • Pierre Corvol et Nicolas Postel-Vinay, L'arbre vasculaire. Les nouvelles voies de guérison, Éditions Odile Jacob, Paris, 2008.
  • Pierre Corvol et Nicolas Postel-Vinay, Le Retour du Dr Knock, Éditions Odile Jacob, Paris, 2000.

Principaux articles

  • Galen F.X., Devaux C., Guyene T., Ménard J. and Corvol P. “Multiple forms of human renin: purification and characterization”. J. Biol. Chem. 254 : 4848-4855, 1979.
  • Bouhnik J., Clauser E., Strosberg D., Frenoy J.P., Ménard J. and Corvol P. “Rat angiotensinogen and des (angiotensin I)angiotensinogen: Purification, characterization and partial sequencing”. Biochemistry 20 : 7010-7015, 1981.
  • Rougeon F., Chambraud B., Foote S., Panthier J.J., Nageotte R. and Corvol P. “Molecular cloning of a mousesubmaxillary gland renin cDNA fragment”. Proc. Natl. Acad. Sci. 78 : 6367-6371, 1981.
  • Panthier J.J., Foote S., Chambraud B., Strosberg A.D., Corvol P. and Rougeon F. “Complete amino-acid sequence and maturation of the mouse submaxillary gland renin precursor”. Nature 298 : 90-92, 1982.
  • Galen F.X., Corvol M.T., Devaux C., Gubler M.C., Mounier F., Camilleri J.P., Houot A.M., Ménard J. and Corvol P. “Renin biosynthesis by human tumoral juxtaglomerular cells: evidence for a renin precursor”. J. Clin. Invest. 73 : 1144-1155, 1984.
  • Evin G., Devin J., Castro B., Ménard J. and Corvol P. “Synthesis of peptides related to the prosegment of mouse submaxillary renin precursor: a new approach to renin inhibitors”. Proc. Natl. Acad. Sci. USA 81 : 48-52, 1984.
  • Campbell D.J., Bouhnik J., Ménard J. and Corvol P. “Identity of angiotensinogen precursor of rat brain and liver”. Nature 308 : 206-208, 1984.
  • Campbell D.J., Bouhnik J., Coezy E., Ménard J. and Corvol P. “Characterization of precursor and secreted forms of human angiotensinogen”. J. Clin. Invest. 75 : 1880-1893, 1985.
  • Cumin F., Evin G., Fehrentz J.A., Seyzer R., Castro B., Ménard J. and Corvol P. “Inhibition of human renin by synthetic peptides derived from its prosegment”. J. Biol. Chem. 260 (16) : 9154-9157, 1985.
  • Pinet F., Corvol M.T., Dench F., Bourguignon J., Feunteun J., Ménard J. and Corvol P. “Isolation of renin producing human cells by transfection with three SV40 mutants”. Proc. Natl. Acad. Sci USA 82 : 8503-8507, 1985.
  • Pinet F., Mizrahi J., Laboulandine I., Ménard J. and Corvol P. “Regulation of prorenin secretion in human transfected juxtaglomerular cells”. J. Clin. Invest. 80 : 724-731, 1987.
  • Soubrier F., Alhenc-Gelas F., Hubert C., Allegrini J., John M., Tregear G. and Corvol P. “Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning”. Proc. Natl. Acad. Sci. USA 85 : 9386-9390, 1988.
  • Gaillard I., Clauser E., and Corvol P. “Structure of human angiotensinogen gene”. DNA 8 : 87-99, 1989.
  • Soubrier F., Jeunemaitre X., Rigt B., Houot A.M., Cambien F. and Corvol P. “Similar frequencies of renin gene RFLPs in hypertensives and normotensives”. Hypertension 16 : 712-717, 1990.
  • Rigat B., Hubert C., Alhenc-Gelas F., Cambien F., Corvol P. and Soubrier F. “An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels”. J. Clin. Invest. 86 : 1343-1346, 1990.
  • Wei L., Alhenc-Gelas F., Soubrier F., Michaud A., Corvol P. and Clauser E. “Expression and characterization of recombinant human angiotensin I-converting enzyme”. J. Biol. Chem. 266 : 5540-5546, 1991.
  • Wei L., Alhenc-Gelas F., Corvol P. and Clauser E. “The two homologous domains of human angiotensin I-converting enzyme are both catalytically active”. J. Biol. Chem. 266 : 9002-9008, 1991.
  • Hubert C., Houot A.M., Corvol P. and Soubrier F. “Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene”. J. Biol. Chem. 266 : 15377-15383, 1991.
  • Wei L., Clauser E., Alhenc-Gelas F. and Corvol P. “The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors”. J. Biol. Chem. 267 : 13398-13405, 1992.
  • Jeunemaitre X. Soubrier F., Kotelevtsev Y., Lifton R., Williams C., Charru A., Hunt S., Hopkins P., Williams R., Lalouel J.M. and Corvol P. “Molecular basis of human hypertension: Role of angiotensinogen”. Cell 71 : 169-180, 1992.
  • Beldent V., Michaud A., Wei L., Chauvet M-T. and Corvol P. “Proteolytic release of human angiotensin-converting enzyme. Localization of the cleavage site”. J. Biol. Chem. 268 : 26428-26434, 1993.
  • Sibony M., Gasc J.M., Soubrier F., Alhenc-Gelas F. and Corvol P. “Gene expression and tissue localization of the two isoforms of angiotensin I-converting enzyme”. Hypertension 21 : 827-835, 1993.
  • Bihoreau C., Monnot C., Davies E., Teutsch B., Bernstein K.E., Corvol P. and Clauser E. “Mutation of Asp(74) of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling”. Proc. Natl. Acad. Sci. USA 90 : 5133-5137, 1993.
  • Gasc J.M., Monnot C., Clauser E. and Corvol P. “Coexpression of type 1 angiotensin II receptor (AT1R) and renin mRNAs in juxtaglomerular cells of the rat kidney”. Endocrinology 132 : 2723-2725, 1993.
  • Borensztein P., Germain S., Fuchs S., Philippe J., Corvol P. and Pinet F. “Cis-regulatory elements and trans-acting factors directing basal and cAMP-stimulated human renin gene expression in chorionic cells”. Circ. Res. 74 : 764-773, 1994.
  • Williams T.A., Corvol P. and Soubrier F. “Identification of two active site residues in human angiotensin I-converting enzyme”. J. Biol. Chem. 269 : 29430-29434, 1994.
  • Villard E., Lalau J-D., van Hooft I., Derkx F.H.M., Houot A-M., Pinet F., Corvol P. and Soubrier F. “A mutant renin gene in familial elevation of prorenin”. J. Biol. Chem. 269 : 30307-30312, 1994.
  • Bonnardeaux A., Nadaud S., Charru A., Jeunemaitre X., Corvol P. and Soubrier F. “Exclusion of the endothelial nitric oxyde synthase as a candidate gene for essential hypertension”. Circulation 91 : 96-102, 1995.
  • Rousseau A., Michaud A., Chauvet M-T., Lenfant M. and Corvol P. “The hemoregulatory peptide Acetyl-N-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme”. J. Biol. Chem. 270 : 3656-3661, 1995.
  • Corvol P., Jeunemaitre X., Charru A., Kotelevtsev Y. and Soubrier F. “Role of the renin-angiotensin system in blood pressure regulation and in human hypertension: New insights from molecular genetics”. In: Recent Progress in Hormone Research, Academic Press Inc., vol. 50, pp. 287-308, 1995
  • Corvol P., Williams T.A. and Soubrier F. “Peptidyl dipeptidase A: Angiotensin I-converting enzyme”. In: Methods in Enzymology, Academic Press Inc., Ed. J. Burnett, Vol. 248, pp. 283-305, 1995.
  • Beldent V., Michaud A., Bonnefoy C., Chauvet M-T. and Corvol P. “Cell surface localization of proteolysis of human endothelial angiotensin I-converting enzyme. Effect of the amino-terminal domain in the solubilization process”. J. Biol. Chem. 270 : 28962-28969, 1995.
  • Azizi M., Rousseau A., Ezan E., Guyene T-T., Michelet S., Grognet J-M., Lenfant M., Corvol P. and Ménard J. “Acute angiotensin-converting enzyme inhibitor increases the plasma level of the natural stem-cell regulator N-Acetyl-Seryl-Aspartyl-Lysyl-Proline”. J. Clin. Invest. 97 : 839-844, 1996.
  • Monnot C., Bihoreau C., Conchon S., Curnow K., Corvol P. and Clauser E. “Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling”. J. Biol. Chem. 271 : 1507-1513, 1996.
  • Zini S., Fournié-Zaluski M-C., Chauvel E., Roques B.P., Corvol P. and Llorens-Cortes C. “Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: Predominant role of angiotensin III in the control of vasopressin release”. Proc. natl. Acad. Sci. USA 93 : 11968-11973, 1996.
  • Williams T.A., Gouttaya M., Tougard C., Michaud A., Chauvet M-T. and Corvol P. “Cleavage-secretion of angiotensin I-converting enzyme in yeast”. Mol. Cell. Endocrinol. 128 : 39-45, 1997.
  • Le Moullec J.-M., Jouquey S., Corvol P. and Pinet F. “A sensitive RT/PCR assay for measuring the effects of dehydration and gestation in rat AVP and OT mRNAs”. Mol. Cell. Endocrinol. 128 : 151-159, 1997.
  • Germain S., Philippe J., Fuchs S., Lengronne A., Corvol P. and Pinet F. “Regulation of human renin secretion and gene transcription in Calu-6 cells”. FEBS Lett. 407 : 177-183, 1997.
  • Davies E., Bonnardeaux A, Plouin P.F., Corvol P. and Clauser E. “The role of angiotensin II (type 1) receptor in primary hyperaldosteronism” J. Clin. Endocrinol. Metab 82 : 611-615, 1997.
  • Esther C.R., Marino E.M., Howard T.E., Michaud A., Corvol P., Capecchi M.R. and Bernstein K.E. “The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice”. J. Clin. Invest. 99 : 2375-2385, 1997.
  • Conchon S., Barrault M-B., Miserey S., Corvol P. and Clauser E. “The C-terminal third intracellular loop of the rat AT1A angiotensin II receptor plays a key role in G protein coupling specificity and transduction of the mitogenic signal”. J. Biol. Chem. 272 : 25566-25572, 1997.
  • Michaud A., Williams T-A., Chauvet M-T. and Corvol P. “Substrate dependence of Angiotensin I-converting enzyme inhibition: captopril displays a partial selectivity for inhibition of N-acetyl-seryl-aspartyl-lysyl-proline hydrolysis compared with that of angiotensin I”. Mol. Pharmacol. 51 : 1070-1076, 1997.
  • Corvol P. and Jeunemaitre X. “Molecular genetics of human hypertension: role of angiotensinogen”. Endocr. Rev. 18 : 662-677, 1997.
  • Brand M., Le Moullec J-M., Corvol P. and Gasc J-M. “Ontogeny of endothelins-1 and -3, their receptors and endothelin converting enzyme-1 in the early human embryo”. J. Clin. Invest. 101 : 549-559, 1998.
  • Germain S., Bonnet F., Philippe J., Fuchs S., Corvol P. and Pinet F. “A novel distal enhancer confers chorionic expression on the human renin gene”. J. Biol. Chem. 273 : 25292-25300, 1998.
  • Kempf H., Linares C., Corvol P. and Gasc J-M. “Pharmacological inactivation of the endothelin type A receptor in the early chick embryo: a model of mispatterning of the branchial arch derivatives”. Development 125 : 4931-4941, 1998.
  • Hubert C., Gasc J-M., Berger S., Schutz G. and Corvol P. “Effects of mineralocorticoid receptor genes disruption on the components of the renin-angiotensin system in 8-day old mice”. Mol. Endocrinol. 13 : 297-306, 1999.
  • Dive V., Cotton J., Yiotakis A., Michaud A., Vissiliou S., Jiracek J., Vazeux G., Chauvet M-T., Cuniasse P. and Corvol P. “RXP407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites”. Proc. Natl. Acad. Sci. USA 96 : 4330-4335, 1999.
  • Reaux A., Fournie-Zaluski M-C., David C., Zini S., Roques B.P., Corvol P. and Llorens-Cortes C. “Aminopeptidase A inhibitors as potential central antihypertensive agents”. Proc. Natl. Acad. Sci. USA 96 : 13415-13420, 1999.
  • Celerier J., Schmid G., Le Caer J-P., Gimenez-Roqueplo A-P., Bur D., Friedlein A., Langen H., Corvol P. and Jeunemaitre X. “Characterization of a human angiotensinogen cleaved in its reactive center loop by a proteolytic activity from chinese hamster ovary cells”. J. Biol. Chem. 275 : 10648-10654, 2000.
  • Iturrioz X., Vazeux G., Célérier J., Corvol P. and Llorens-Cortes C. “Histidine 450 plays a critical role in catalysis and, with Ca2+, contributes to te substrate specificity of aminopeptidase A”. Biochemistry 39 : 3061-3068, 2000.
  • Disse-Nicodeme S., Achard J.M., Desitter I., Houot A.M., Fournier A., Corvol P. and Jeunemaitre X. “A new locus on chromosome 12p13.3 for pseudohypoaldosteronism type II, an autosomal dominant form of hypertension”. Am. J. Hum. Genet. 67 : 302-310, 2000.
  • Parnot C., Bardin S., Miserey-Lenkei S., Guédin D., Corvol P. and Clauser E. “Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay”. Proc. Natl. Acad. Sci. USA 97 : 7615-7620, 2000.
  • Coates D., Isaac R.E., Cotton J., Siviter R., Williams T.A., Shirras A., Corvol P. and Dive V. “Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme”. Biochemistry 39 : 8963-3969, 2000.