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Presentation Individual health is the outcome of dynamic interactions between the environment and a diversity of organisms, such as human cells, bacteria, fungi, or viruses. We use tools and concepts from ecology and evolution to analyse the functioning …

Presentation Our laboratory studies vascular and neuronal development, with particular interests in mechanisms that direct patterning and guidance. Specialized endothelial cells (EC) called tip cells located at the extremities of growing capillary sprouts …

Presentation The structure of enzymes in complex with macromolecular substrates (proteins, DNAs, RNAs...) and the understanding of their mechanisms of recognition and action are still formidable challenges in biological chemistry today. We are …

Presentation A whole series of original molecular complexes, most often bioinspired in the sense that their structure is reminiscent of certain enzyme active sites, are being synthesized and studied for their catalytic properties. Some of them have …

Presentation Ubiquinone is an essential cofactor in bioenergetics. Yet its biosynthesis is still poorly understood, despite the fact that it represents a real chemical challenge due to its structural complexity and water insolubility. For several years, …