Abstract of Alejandro Perez Luna's talk
Organo(di)metal reagents for organic synthesis
The development of new organic synthesis processes that meet economic needs while respecting the environment is both a major challenge for organometallic chemistry and a formidable driver of innovation. In this context, organozincs are the reagents of choice, as they are low-toxicity, low-cost and highly tolerant of many functional groups. They are also particularly interesting for their dual radical and polar reactivity. In the laboratory, we are interested in the synthesis of double-metallized organozincs in order to obtain dicarbanionic units whose dinucleophilic character can be exploited sequentially in the same reaction medium. In particular, we have developed new silyl- and germylzincation reactions of alkynes to obtain dimetalized alkenes, the preparation of dimetalized allenes by rearrangement of silylmetallates derived from acetylenic epoxides, or the enantioselective activation of gem-diorganozincs.
Generation of carbanions by extrusion of N2 : history and applications (title of Clément Chauvier's talk)
