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In the event of injury to the spinal cord, the axons connecting the brain to the spinal cord can be interrupted, leading to paralysis. In higher vertebrates, this paralysis is often permanent, as the axons are unable to regenerate. The mechanisms that …

Abstract The processing of information by brain circuits is the central question of neuroscience. The fate of visual signals at the level of the cerebral cortex is the prototype. After the deciphering of the primary visual cortex and the exploration of …

In the embryo, axon elongation is guided by chemoattractant and chemorepulsive molecules. In the years 1990, four canonical families of proteins involved in the orientation of growing axons were discovered : netrins, semaphorins, ephrins and slit …