My name is Alexandre Mayran. I did my PhD in Montreal, Canada, at the IRCM in the laboratory of Pr Jacques Drouin. There, I worked on the interplay between cell fate specification and chromatin remodelling driven by pioneer transcription factors using different model systems (pituitary and limb buds). In 2019, I joined the laboratory of Pr Duboule as a postdoctoral fellow where I secured funding from Human Frontier Science Program to work on gastruloids, a 3D model of mammalian embryos. I study mechanisms underlying self-organization, its link with cell fate specification and how to complexify these artificial embryos.