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Harry Falk
The Prajnaparamita Manuscript from Gandhara-New Light on the Genesis of Mahayana Buddhism
Harry Falk
The Prajnaparamita Manuscript from Gandhara-New Light on the Genesis of Mahayana Buddhism
Guest lecturer
Event
11:00am - 12:00pm
Syria in the 3rd millennium BC from the Ebla archives
Jean-Marie Durand, chair Assyriology
Syria in the 3rd millennium BC from the Ebla archives
Jean-Marie Durand, chair Assyriology
Guest lecturer
Series
Texts from the Archives of the G royal palace at Ebla (Tell Mardikh, 60 km south-west of Aleppo, in northern Syria) from the xxive century BC now make it possible to write the political, economic and social history of Syria in the third millennium BC, …
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Event
In the Christian tradition, the resurrection symbolizes the overcoming of death and the triumph of a second life for the individual redeemed forever. The new religion of salvation also attaches great importance to the gratitude that the living are obliged …
5:00 - 6:00pm
Stephan Beck
What lectures can be drawn from the pinball game conducted on the cancer methylome ?
Stephan Beck
What lectures can be drawn from the pinball game conducted on the cancer methylome ?
Symposium
Event
Abstract The discovery of numerous and frequent mutations in epigenome modifiers have highlighted the importance of epigenetic mechanisms in cancer. In addition, epimutations such as aberrant DNA met hylation have been reported to constitute the most …
9:00 - 9:45am
Event
References Ng S.F., Lin R.C., Laybutt D.R., Barres R., Owens J.A., Morris M.J., "Chronic high-fat diet in fathers programs -celldysfunction in fernale rat offspring", Nature , 2010 Oct 21;467(7318):963-6 Rando O.J., "Daddy issues: paternal effects on …
9:45 - 10:30am
Event
Abstract Histone modifications can regulate many chromatin-related processes such as transcription, replication and DNA-repair, they can demarcate the genomic position of regulatory elements such as enhancers and may be involved in disease processes if …
11:35am - 12:05pm
Event
12:05 - 12:50pm
Event
Abstract Although the H19 gene was discovered in 1984, its precise function is still relatively poorly understood. lt is located on mouse chromosome 7, close to the Jg/2 (insulin-like growth factor 2) gene, in an imprinted locus. The maternal allele …
3:30 - 3:50pm
Event
Abstract Germ cell differentiation allows the production of mature gametes that are competent for fertilization and that carry genetic but also non-genetically encoded information. DNA methylation is an autonomous epigenetic mark, with intrinsic stability …
2:45 - 3:30pm
Event
Abstract Epigenetic regulation plays essential roles in development and disease and may become perturbed as a consequence of dietary and environ mental factors [1] . One of the best characterized epigenetic phenomena in ma mmals is genomic imprinting, a …
4:50 - 5:35pm
Event
Abstract Environmental factors during early life are critical for the Jater metabolic health of the individual and of future progeny. Using a mouse model of maternal calorie restriction during pregnancy affecting the metabolic physiology of two …
2:00 - 2:45pm
Anne-Valerie Gendrel
Random expression of monoallelic genes during development and in pathology
Anne-Valerie Gendrel
Random expression of monoallelic genes during development and in pathology
Symposium
Event
Abstract The majority of autosomal genes in mamma are believed to be expressed from both alleles. However a number of imprinted genes exist and an increasing number of loci may be expressed monoallelically in a random fashion, similar to the X chromosome …
5:35 - 5:55pm
Event
Abstract In mammals, the dosage imbalance between males and females resulting from the presence of heteromorphie sex chromosomes is compensated for by the inactivation of one X-chromosome in females. This process, which is initiated during the early …
5:55 - 6:25pm
Event
References Eustermann S., Yang J.C., Law M.J., Amos R., Chapman L.M., Jelinska C., Garrick D., Clynes D., Gibbons R.J., Rhodes D., Higgs D.R., Neuhaus D., "Combinatorial readout of histone H3 modifications specifies localization of ATRX to …
10:15 - 11:00am
Event
Abstract Position effect variegation (PEY) is an archetypal epigenetic phenomenon in which a gene abnormally located close to heterochromatin is stochastically silenced in a proportion of cells that would normally express it. First described in Drosophila …
11:40am - 12:25pm
Event
Abstract Epigenetic regulation of cognition is an emerging field in Neuroscience. However, the identity of crucial regulators and underlying molecular mechanisms are poorly understood. Excellent candidates are epigenetic genes that are mutated in …
11:20 - 11:40am
Event
The event took place at the ENS. Documents and media Go to audio …
2:30 - 3:00pm
Event
The event took place at the ENS. Documents and media Go to audio …
3:30 - 4:00pm
Event
The event took place at the ENS. Documents and media Go to audio …
11:30am - 12:00pm