10:15 - 11:00am
Symposium
Not recorded

Role of the ATRX/DACXX/H3.3 chromatin remodeling complex in human inherited and acquired genetic diseases

Doug Higgs
10:15 - 11:00am
Amphithéâtre Guillaume Budé, Site Marcelin Berthelot
Open to all, subject to availability
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References

Eustermann S., Yang J.C., Law M.J., Amos R., Chapman L.M., Jelinska C., Garrick D., Clynes D., Gibbons R.J., Rhodes D., Higgs D.R., Neuhaus D., "Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin", Nat Struct Mol Biol, 2011 Jun 12;18(7):777-82.

Law M.J., Lower K.M., Voon H.P., ... Higgs D.R., Gibbons R.J., "ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner", Cell, 2010 Oct 29;143(3):367-78.

Goldberg A.D., Banaszynski L.A., ... Higgs D.R., Cristea I.M., Urnov F.D., Zheng D., Allis C.D., "Distinct factors control histone variant H3.3 localization at specifie genomic regions", Cell, 2010 Mar 5;1 40(5):678-91.

Steensma D.P., Gibbons R.J., Higgs D.R., "Acquired alpha-thalassemia in association with myelodysplastic syndrome and other hematologic malignancies", Blood, 2005 Jan 15;105(2):443-52.

Speaker(s)

Doug Higgs

MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe, Hospital Oxford UK

Events

Symposium
9:30 - 10:15am
Not recorded
Symposium
9:45 - 10:30am
Not recorded
Symposium
11:35am - 12:05pm
Not recorded