Ouvrages et articles

Livres

Prochiantz A., Qu'est-ce que le vivant ?, Éditions du Seuil, Paris, 2012, coll. « Les Livres du nouveau monde ».
Prochiantz A. (dir.), Darwin : 200 ans, Paris, Odile Jacob – Collège de France, 2010.
Prochiantz A., Géométries du vivant, Collège de France/Fayard, Paris, 2007.
Peyret J.-F. et Prochiantz A., Les Variations Darwin, Éditions Odile Jacob, Paris, 2005.
Peyret J.-F. et Prochiantz A., La Génisse et le Pythagoricien, Éditions Odile Jacob, Paris, 2002.
Prochiantz A., Machine-esprit, Éditions Odile Jacob, Paris, 2001.
Prochiantz A., Les anatomies de la pensée, Éditions Odile Jacob, Paris, 1997.
Prochiantz A., La biologie dans le boudoir, Éditions Odile Jacob, Paris, 1995.
Prochiantz A., Claude Bernard : la révolution physiologique, PUF, 1990.
Prochiantz A., La construction du cerveau, Hachette, 1989.
Prochiantz A., Les stratégies de l'embryon, PUF, 1987.

Principaux articles

Spatazza J., Lee H.H., Di Nardo A.A., Tibaldi L., Joliot A., Hensch T.K. & Prochiantz A. (2013), Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity. Cell Report, Volume 3, Issue 6,1815-1823.
Despras G., Bernard C., Perrot A., Cattiaux L., Prochiantz A., Lortat-Jacob H. & Mallet J.-M. (2013), Toward libraries of biotinylated chondroitin sulfate analogues: from synthesis to in vivo studies. Chemistry 19, 531-540.
Spatazza J., Di Lullo E., Joliot A., Dupont E., Moya K.L. & Prochiantz A. (2013), Homeoprotein signaling in development, health, and disease: a shaking of dogmas offers challenges and promises from bench to bed. Pharmacol Rev. Jan 8;65(1):90-104.
Beurdeley M., Spatazza J., Lee H., Sugiyama S., Bernard C., Di Nardo A., Hensch T. & Prochiantz A. (2012), Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex, The Journal of Neuroscience, July4, 2012-32(27): 9429-9437.
Stettler O., Joshi R.L., Wizenmann A., Reingruber J., Holcman D., Bouillot C., Castagner F., Prochiantz A. & Moya K.L. (2012), Engrailed homeoprotein recruits the adenosine A1 receptor to potentiate ephrin A5 function in retinal growth cones. Development. Jan; 139(1):215-24.
Layalle S., Volovitch M., Mugat B., Bonneaud N., Parmentier M.L., Prochiantz A., Joliot A. & Maschat F. (2011), Engrailed homeoprotein acts as a signaling molecule in the developing fly. Development, Jun; 138(11): 2315-23.
Di Lullo E., Haton C., Le Poupon C., Volovitch M., Joliot A., Thomas J.-L. & Prochiantz A. (2011), Paracrine Pax6 activity regulates oligodendrocyte precursor cell migration in the chick embryonic neural tube. Development 138, 4991-5001.
Torero Ibad R., Rheey J., Mrejen S., Forster V., Picaud S., Prochiantz A. & Moya K.L. (2011), Otx2 promotes the survival of damaged adult retinal ganglion cells and protects against excitotoxic loss of visual acuity in vivo. J. Neurosci., Apr 6;31(14):5495-503.
Alvarez-Fischer D., Fuchs J., Castagner F., Stettler O., Massiani-Beaudoin O., Moya K.L., Bouillot C., Oertel W.H., Lombès A., Faigle W., Joshi R.L., Hartmann A. & Prochiantz A. (2011), Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. Nat.Neurosci., Sep 14: 1260-66.
Wizenmann A., Brunet I., Lam J., Sonnier L., Beurdeley M., Zarbalis K., Weisenhorn-Vogt D., Weinl C., Dwivedy A., Joliot A., Wurst W., Holt* C. & Prochiantz* A. (2009), Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo. Neuron, 64, 355-366.
(*co-corresponding authors)
De Toni A., Zbinden M., Epstein J.A., Ruiz I Altaba A., Prochiantz A. & Caillé I. (2008), Regulation of survival in adult hippocampal stem cell lineages by the homeodomain only protein HOP. Neural Dev, 3, 13.
Kasatkin V., Prochiantz A. & Holcman D. (2008), Morphogenetic gradients and the stability of boundaries between neighbouring morphogenetic regions. Bulletin of Mathematical Biology, 70, 156-178.
Sugiyama S., Di Nardo A., Aizawa S., Matsuo I., Volovitch M., Prochiantz* A. & Hensch* T.K. (2008), Experience-dependent transport of Otx2 homeoprotein in the visual pathway activates postnatal cortical plasticity. Cell, 134, 508-520.
Brunet I., Di Nardo A., Sonnier L., Beurdeley M. & Prochiantz A. (2007), Shaping neural pathways with messenger homeoproteins. Trends in Neurosciences, 30, 260-267.
Dupont E., Prochiantz A. & Joliot A. (2007), Identification of a signal peptide for unconventional secretion. J Biol Chem, 282, 8894-9000.
Yves Agid, György Buzsáki, David M. Diamond, Richard Frackowiak, Jay Giedd, Jean-Antoine Girault, Anthony Grace, Jeremy J. Lambert, Husseini Manji, Helen Mayberg, Maurizio Popoli, Alain Prochiantz, Gal Richter-Levin, Peter Somogyi, Michael Spedding, Per Svenningsson & Daniel Weinberger (2007), How can drug discovery for psychiatric disorders be improved? Nature Reviews Drug Discovery, 6, 189-201.
Sonnier L., Le Pen G., Hartman A., Bizot J.-C., Trovero F., Krebs M.-O.& Prochiantz A. (2007), Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1: a new genetic model for neurological and psychiatric disorders. J Neurosci, 27, 1063-1071.
Lesaffre B., Joliot A., Prochiantz A. & Volovitch M. (2007), Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish. Neural Development, 2, 2.
Prochiantz A. (2007), A protein fusion a day keeps the aggregates away. Molecular Therapy, 15, 226-227.
Prochiantz A. (2007), For protein transduction, chemistry can win over biology. Nat Methods, 4, 119-120.
Holcman D., Kasatkin V. & Prochiantz A. (2007), Modeling homeoprotein intercellular transfer unveils a parsimonious mechaniss for gradient and boundary formation in early brain development. J Theor Biol, 249, 503-517.
Di Nardo A., Nedelec S. (co-first), Trembleau A., Volovitch M., Prochiantz* A. & Montesinos M.L. (2007), Dendritic localization and activity-dependent translation of En1 homeodomain transcription factor mRNA. Mol Cell Neurosci, 35, 230-236.
Linsik M.F., Christiaens B., Vandekerckhove J., Prochiantz A. & Rosseneu M. (2005), Penetratin-membrane association: W48/R52/W56 shield the peptide from the aqueous phase. Biophys J, 88, 1-14.
Madeira A., Pommet J.M., Prochiantz A. & Allinquant B. (2005), SET protein (TAF1ß, I2PP2A) is involved in neuronal apoptosis induced by an Amyloid Precursor Protein cytoplasmic subdomain. FASEB J, 19, 1905-1907.
Brunet I., Weinl C., Piper M., Trembleau A., Volovitch M., Harris B., Prochiantz* A., & Holt* C. (2005), Engrailed-2 guides retinal axons. Nature, 438, 94-98.
Joliot A. & Prochiantz A. (2004), Transduction peptides, from technology to physiology. Nature Cell Biology, 6, 189-196.
Prochiantz A. and Joliot A. (2003), Can transcription factors function as cell-cell signaling molecules? Nature reviews, Molecular Cell Biology, 4, 814-818.
Maizel A., Tassetto M., Filhol O., Cochet C., Prochiantz A. & Joliot A. (2002), Engrailed homeoprotein secretion is a regulated process. Development, 129, 3545-3553.
Prochiantz A. (2000), Messenger proteins: homeoproteins, TAT and others. Curr. Opin. Cell Biol., 12, 400-406.
Maizel A., Bensaude O., Prochiantz A. & Joliot A. (1999), A short region of its homeodomain is necessary for Engrailed nuclear export and secretion. Development, 126, 3183-3190.
Joliot A., Maizel A., Rosenberg D., Trembleau A., Volovitch M. & Prochiantz A. (1998), Identification of a signal sequence necessary for the unconventional secretion of Engrailed Homeoprotein. Curr. Biol., 8, 856-863.
Derossi D., Chassaing G. & Prochiantz A. (1998), Trojan peptides: the penetratin system for intracellular delivery. Trends in Cell Biol., 8, 84-87.
Joliot A., Trembleau A., Raposo G., Calvet S., Volovitch M. & Prochiantz A. (1997), Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties. Development, 124, 1865-1875.
Prochiantz A. (1996), Getting hydrophobic compounds into cells: lessons from homeopeptides. Curr. Opin. in Neurobiol., 6, 629-634.
Derossi D., Joliot A.H., Chassaing G. & Prochiantz A. (1994), The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem., 269, 10444-10455.
Le Roux I., Joliot A.H., Bloch-Gallego E., Prochiantz A. & Volovitch M. (1993), Neurotrophic activity of the Antennapedia homeodomain depends on its specific DNA-binding properties. Proc. Natl. Acad. Sci. USA, 90, 9120-9124.
Joliot A., Pernelle C., Deagostini-Bazin H. & Prochiantz A. (1991), Antennapedia homeobox peptide regulates neural morphogenesis. Proc. Natl. Acad. Sci. USA, 88, 1864-1868.
Ayala J., Touchot N., Zahraoui A., Tavitian A. & Prochiantz A. (1990), The product of rab2p, a small GTP-binding protein, increases neuronal adhesion & neurite growth in vitro. Neuron, 4, 797-805.
Nowak L., Bregestovski P., Ascher P., Herbet A. & Prochiantz A. (1984), Magnesium gates glutamate-activated channels in mouse central neurones. Nature, 307, 462-465.
Denis-Donini S., Glowinski J. & Prochiantz A. (1984), Glial heterogeneity may define the three-dimensional shape of mesencephalic dopaminergic neurons. Nature, 307, 641-643.
Prochiantz A., Daguet M.-C., Herbet A. & Glowinski J. (1981), Specific stimulation of in vitro maturation of dopaminergic neurons by striatal membranes. Nature, 293, 570-572.
di Porzio U., Daguet M.-C., Glowinski J. & Prochiantz A. (1980), Effect of striatal target cells on in vitro maturation of mesencephalic dopaminergic neurons grown in serum-free conditions. Nature, 288, 370-373.