Ouvrages et articles

Livres

  • Prochiantz A., Qu'est-ce que le vivant ?, Éditions du Seuil, Paris, 2012, coll. « Les Livres du nouveau monde ».

  • Prochiantz A. (dir.), Darwin : 200 ans, Paris, Odile  Jacob – Collège de France, 2010.

  • Prochiantz A., Géométries du vivant, Collège de France/Fayard, Paris, 2007.

  • Peyret J.-F. et Prochiantz A., Les Variations Darwin, Éditions Odile Jacob, Paris, 2005.

  • Peyret J.-F. et Prochiantz A., La Génisse et le Pythagoricien, Éditions Odile Jacob, Paris, 2002.

  • Prochiantz A., Machine-esprit, Éditions Odile Jacob, Paris, 2001.

  • Prochiantz A., Les anatomies de la pensée, Éditions Odile Jacob, Paris, 1997.

  • Prochiantz A., La biologie dans le boudoir, Éditions Odile Jacob, Paris, 1995.

  • Prochiantz A., Claude Bernard : la révolution physiologique, PUF, 1990.

  • Prochiantz A., La construction du cerveau, Hachette, 1989.

  • Prochiantz A., Les stratégies de l'embryon, PUF, 1987.

Principaux articles

  • Spatazza J., Lee H.H., Di Nardo A.A., Tibaldi L., Joliot A., Hensch T.K. & Prochiantz A. (2013), Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity. Cell Report, Volume 3, Issue 6,1815-1823.

  • Despras G., Bernard C., Perrot A., Cattiaux L., Prochiantz A., Lortat-Jacob H. & Mallet J.-M. (2013), Toward libraries of biotinylated chondroitin sulfate analogues: from synthesis to in vivo studies. Chemistry 19, 531-540.

  • Spatazza J., Di Lullo E., Joliot A., Dupont E., Moya K.L. & Prochiantz A. (2013), Homeoprotein signaling in development, health, and disease: a shaking of dogmas offers challenges and promises from bench to bed. Pharmacol Rev. Jan 8;65(1):90-104.

  • Beurdeley M., Spatazza J., Lee H., Sugiyama S., Bernard C., Di Nardo A., Hensch T. & Prochiantz A. (2012), Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex, The Journal of Neuroscience, July4, 2012-32(27): 9429-9437.

  • Stettler O., Joshi R.L., Wizenmann A., Reingruber J., Holcman D., Bouillot C., Castagner F., Prochiantz A. & Moya K.L. (2012), Engrailed homeoprotein recruits the adenosine A1 receptor to potentiate ephrin A5 function in retinal growth cones. Development. Jan; 139(1):215-24.

  • Layalle S., Volovitch M., Mugat B., Bonneaud N., Parmentier M.L., Prochiantz A., Joliot A. & Maschat F. (2011), Engrailed homeoprotein acts as a signaling molecule in the developing fly. Development, Jun; 138(11): 2315-23.

  • Di Lullo E., Haton C., Le Poupon C., Volovitch M., Joliot A., Thomas J.-L. & Prochiantz A. (2011), Paracrine Pax6 activity regulates oligodendrocyte precursor cell migration in the chick embryonic neural tube. Development 138, 4991-5001.

  • Torero Ibad R., Rheey J., Mrejen S., Forster V., Picaud S., Prochiantz A. & Moya K.L. (2011), Otx2 promotes the survival of damaged adult retinal ganglion cells and protects against excitotoxic loss of visual acuity in vivo. J. Neurosci., Apr 6;31(14):5495-503.

  • Alvarez-Fischer D., Fuchs J., Castagner F., Stettler O., Massiani-Beaudoin O., Moya K.L., Bouillot C., Oertel W.H., Lombès A., Faigle W., Joshi R.L., Hartmann A. & Prochiantz A. (2011), Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. Nat.Neurosci., Sep 14: 1260-66.

  • Wizenmann A., Brunet I., Lam J., Sonnier L., Beurdeley M., Zarbalis K., Weisenhorn-Vogt D., Weinl C., Dwivedy A., Joliot A., Wurst W., Holt* C. & Prochiantz* A. (2009), Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo. Neuron, 64, 355-366.
    (*co-corresponding authors)

  • De Toni A., Zbinden M., Epstein J.A., Ruiz I Altaba A., Prochiantz A. & Caillé I. (2008), Regulation of survival in adult hippocampal stem cell lineages by the homeodomain only protein HOP. Neural Dev, 3, 13.

  • Kasatkin V., Prochiantz A. & Holcman D. (2008), Morphogenetic gradients and the stability of boundaries between neighbouring morphogenetic regions. Bulletin of Mathematical Biology, 70, 156-178.

  • Sugiyama S., Di Nardo A., Aizawa S., Matsuo I., Volovitch M., Prochiantz* A. & Hensch* T.K. (2008), Experience-dependent transport of Otx2 homeoprotein in the visual pathway activates postnatal cortical plasticity. Cell, 134, 508-520.

  • Brunet I., Di Nardo A., Sonnier L., Beurdeley M. & Prochiantz A. (2007), Shaping neural pathways with messenger homeoproteins. Trends in Neurosciences, 30, 260-267.

  • Dupont E., Prochiantz A. & Joliot A. (2007), Identification of a signal peptide for unconventional secretion. J Biol Chem, 282, 8894-9000.

  • Yves Agid, György Buzsáki, David M. Diamond, Richard Frackowiak, Jay Giedd, Jean-Antoine Girault, Anthony Grace, Jeremy J. Lambert, Husseini Manji, Helen Mayberg, Maurizio Popoli, Alain Prochiantz, Gal Richter-Levin, Peter Somogyi, Michael Spedding, Per Svenningsson & Daniel Weinberger (2007), How can drug discovery for psychiatric disorders be improved? Nature Reviews Drug Discovery, 6, 189-201.

  • Sonnier L., Le Pen G., Hartman A., Bizot J.-C., Trovero F., Krebs M.-O.& Prochiantz A. (2007), Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1: a new genetic model for neurological and psychiatric disorders. J Neurosci, 27, 1063-1071.

  • Lesaffre B., Joliot A., Prochiantz A. & Volovitch M. (2007), Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish. Neural Development, 2, 2.

  • Prochiantz A. (2007), A protein fusion a day keeps the aggregates away. Molecular Therapy, 15, 226-227.

  • Prochiantz A. (2007), For protein transduction, chemistry can win over biology. Nat Methods, 4, 119-120.

  • Holcman D., Kasatkin V. & Prochiantz A. (2007), Modeling homeoprotein intercellular transfer unveils a parsimonious mechaniss for gradient and boundary formation in early brain development. J Theor Biol, 249, 503-517.

  • Di Nardo A., Nedelec S. (co-first), Trembleau A., Volovitch M., Prochiantz* A. & Montesinos M.L. (2007), Dendritic localization and activity-dependent translation of En1 homeodomain transcription factor mRNA. Mol Cell Neurosci, 35, 230-236.

  • Linsik M.F., Christiaens B., Vandekerckhove J., Prochiantz A. & Rosseneu M. (2005), Penetratin-membrane association: W48/R52/W56 shield the peptide from the aqueous phase. Biophys J, 88, 1-14.

  • Madeira A., Pommet J.M., Prochiantz A. & Allinquant B. (2005), SET protein (TAF1ß, I2PP2A) is involved in neuronal apoptosis induced by an Amyloid Precursor Protein cytoplasmic subdomain. FASEB J, 19, 1905-1907.

  • Brunet I., Weinl C., Piper M., Trembleau A., Volovitch M., Harris B., Prochiantz* A., & Holt* C. (2005), Engrailed-2 guides retinal axons. Nature, 438, 94-98.

  • Joliot A. & Prochiantz A. (2004), Transduction peptides, from technology to physiology. Nature Cell Biology, 6, 189-196.

  • Prochiantz A. and Joliot A. (2003), Can transcription factors function as cell-cell signaling molecules? Nature reviews, Molecular Cell Biology, 4, 814-818.

  • Maizel A., Tassetto M., Filhol O., Cochet C., Prochiantz A. & Joliot A. (2002), Engrailed homeoprotein secretion is a regulated process. Development, 129, 3545-3553.

  • Prochiantz A. (2000), Messenger proteins: homeoproteins, TAT and others. Curr. Opin. Cell Biol., 12, 400-406.

  • Maizel A., Bensaude O., Prochiantz A. & Joliot A. (1999), A short region of its homeodomain is necessary for Engrailed nuclear export and secretion. Development, 126, 3183-3190.

  • Joliot A., Maizel A., Rosenberg D., Trembleau A., Volovitch M. & Prochiantz A. (1998), Identification of a signal sequence necessary for the unconventional secretion of Engrailed Homeoprotein. Curr. Biol., 8, 856-863.

  • Derossi D., Chassaing G. & Prochiantz A. (1998), Trojan peptides: the penetratin system for intracellular delivery. Trends in Cell Biol., 8, 84-87.

  • Joliot A., Trembleau A., Raposo G., Calvet S., Volovitch M. & Prochiantz A. (1997), Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties. Development, 124, 1865-1875.

  • Prochiantz A. (1996), Getting hydrophobic compounds into cells: lessons from homeopeptides. Curr. Opin. in Neurobiol., 6, 629-634.

  • Derossi D., Joliot A.H., Chassaing G. & Prochiantz A. (1994), The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem., 269, 10444-10455.

  • Le Roux I., Joliot A.H., Bloch-Gallego E., Prochiantz A. & Volovitch M. (1993), Neurotrophic activity of the Antennapedia homeodomain depends on its specific DNA-binding properties. Proc. Natl. Acad. Sci. USA, 90, 9120-9124.

  • Joliot A., Pernelle C., Deagostini-Bazin H. & Prochiantz A. (1991), Antennapedia homeobox peptide regulates neural morphogenesis. Proc. Natl. Acad. Sci. USA, 88, 1864-1868.

  • Ayala J., Touchot N., Zahraoui A., Tavitian A. & Prochiantz A. (1990), The product of rab2p, a small GTP-binding protein, increases neuronal adhesion & neurite growth in vitro. Neuron, 4, 797-805.

  • Nowak L., Bregestovski P., Ascher P., Herbet A. & Prochiantz A. (1984), Magnesium gates glutamate-activated channels in mouse central neurones. Nature, 307, 462-465.

  • Denis-Donini S., Glowinski J. & Prochiantz A. (1984), Glial heterogeneity may define the three-dimensional shape of mesencephalic dopaminergic neurons. Nature, 307, 641-643.

  • Prochiantz A., Daguet M.-C., Herbet A. & Glowinski J. (1981), Specific stimulation of in vitro maturation of dopaminergic neurons by striatal membranes. Nature, 293, 570-572.

  • di Porzio U., Daguet M.-C., Glowinski J. & Prochiantz A. (1980), Effect of striatal target cells on in vitro maturation of mesencephalic dopaminergic neurons grown in serum-free conditions. Nature, 288, 370-373.