Abstract
Visible-light photoredox catalysis provides powerful opportunities for redox transformations under mild conditions;1 however, the development of efficient, low-cost, and metal-free photocatalysts remains a central challenge.1b In this talk, I will present our efforts toward the design of nitrogen-rich organic photocatalysts based on tetrazine2a and heptazine cores,2c,2d and their application in selective oxidative transformations.
I will also discuss stereoselective radical processes, including Smiles-type rearrangements directed by a chiral auxiliary, as well as photocatalyst-free decarboxylative borylation of amino redox-active esters. These methods enable the selective introduction of aryl groups at challenging positions and the efficient incorporation of boron motifs, providing access to β-arylpropamides and α-aminoboron derivatives under mild conditions.
Overall, this lecture highlights how these complementary strategies enable the efficient and sustainable synthesis of high-value bioactive compounds.
