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A major mechanism for achieving specificity in PKA signaling is through localization to specific sites in the cell. One of the most important mechanisms for localizing PKA is through A Kinase Anchoring Proteins (AKAPs) that bind to the dimerization domain …
11:00 to 12:00
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17:00 to 18:00
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The question of the origin of primates has fascinated generations of evolutionary biologists and paleontologists, partly because primates differ from other mammals in fundamental ways, and partly because humans are an integral part of primates. Many of …
15:30 to 16:30
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Abstract To understand how any molecule works requires an understanding of its full-length structure and how it is regulated by other molecules. To achieve this goal requires a variety of techniques that include not only Xray crystallography but also …
11:00 to 12:00
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Three actors will recite poems chosen for them and for the audience by Collège de France professors. Documents and media Download …
20:30 to 21:30
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17:00 to 18:00
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Documents and media Download support …
17:00 to 18:00
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Abstract In this lecture the fundamental allosteric mechanism for regulation of PKA by cAMP will be described. Cyclic AMP serves as a universal intracellular second messenger that translates an extracellular signal into a biological response. The cAMP …
11:00 to 12:00
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11:00 to 12:00
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10:45 to 11:45
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17:00 to 18:00
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11:00 to 12:00
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Abstract This lecture will review the history of protein phosphorylation and then will describe the critical features of active protein kinases. cAMP-dependent protein kinase (PKA), discovered in 1968 and crystallized in 1991, serves as a prototype for …
11:00 to 12:00
Event
11:00 to 12:00
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Documents and media Download support …
17:00 to 18:00