From Statistical Models to Biological Mechanisms of Human Mutation

Shamil Sunyaev is a professor of Medicine and Biomedical Informatics at Harvard Medical School and a Research Geneticist at Brigham & Women’s Hospital. He holds a Distinguished Chair of Computational Genomics. He is also an Associate Member at Broad Institute of MIT and Harvard.
Shamil is a computational geneticist interested in many aspects of genetic variation from the evolutionary, functional and medical genetics perspectives. Population genetics of human deleterious alleles has been one of his major interests. He also develops computational and statistical methods for sequencing studies and methods that use comparative genomics and protein structure to predict the functional effect of mutations.