Articles de recherche

  • "Distinct RhoGEFs activate apical and junctional actomyosin contractility under control of G proteins during epithelial morphogenesis". Alain Garcia De Las Bayonas, Jean-Marc Philippe, Annemarie C. Lellouch, Thomas Lecuit. Current Biology. 2019 Oct 21;29(20):3370-3385.e7. doi: 10.1016/j.cub.2019.08.017

  • Genetic induction and mechanochemical propagation of a morphogenetic wave. Anais Bailles, Claudio Collinet, Jean-Marc Philippe, Pierre-François Lenne, Edwin Munro, Thomas Lecuit. Nature, 2019 Aug;572(7770):467-473. doi: 10.1038/s41586-019-1492-9

  • "Distinct contributions of tensile and shear stress on E-cadherin levels during morphogenesis". Girish Kale, Xingbo Yang, Jean-Marc Philippe, Madhav Mani, Pierre-François Lenne and Thomas Lecuit. Nature Communications, 2018 Nov 27;9(1):5021. doi: 10.1038/s41467-018-07448-8.

  • "Quantitative control of GPCR organization and signaling by endocytosis in epithelial morphogenesis". Jha A, van Zanten T, Philippe J-M, Mayor S and Lecuit T. Current Biology, 2018, 28(10):1570-1584.e6. doi: 10.1016/j.cub.2018.03.068

  • "Strengthen your junctions to resist the force". Lellouch AC, de Las Bayonas AG, Lecuit T. Dev Cell. 2018 Nov 19;47(4):406-407. doi: 10.1016/j.devcel.2018.11.007. PMID: 30458136 (commentary)

  • "Modular activation of Rho1 by GPCR signalling imparts polarized myosin II activation during morphogenesis". Kerridge S, Munjal A, Philippe JM, Jha A, de Las Bayonas AG, Saurin AJ, Lecuit T. Nature Cell Biology. 2016 Mar;18(3):261-70. doi: 10.1038/ncb3302
  • "Local and tissue scale forces drive oriented junction growth during tissue extension". Collinet C, Rauzi M, Lenne PF and Lecuit T. Nature Cell Biology. 2015, AOP 21 sep 2015
  • "A self-organized biomechanical network drives shape changes during tissue morphogenesis". Munjal A, Philippe JM, Edwin Munro and Lecuit T. Nature. 2015 Aug 20;524(7565):351-5
  • "Septins promote F-actin ring formation by crosslinking actin filaments into curved bundles". Mavrakis M, Azou-Gros Y, Tsai FC, Alvarado J, Bertin A, Iv F, Kress A, Brasselet S, Koenderink GH, Lecuit T. Nature Cell Biology. 2014 Apr;16(4):322-34
  • "Oscillation and polarity of E-cadherin asymmetries control actomyosin flow patterns during morphogenesis". Levayer, R and Lecuit T. Developmantal Cell. 2013, Jul 29 ; 26(2):162-75
  • "Adhesion disengagement uncouples intrinsic and extrinsic forces to drive cytokinesis in epithelial tissues". Guillot C, Lecuit T. Developmantal Cell. 2013 Feb 11;24(3):227-41
  • "Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis". Levayer, R., Pelissier, A. and Lecuit, T. Nature Cell Biology 2011, May. 13(5):529-40
  • "Planar polarized actomyosin contractile flows control epithelial junction remodelling". Rauzi, M., Lenne PF., and Lecuit, T. Nature 2010. (Dec 23) 468(7327):1110-4
  • "A two-tiered mechanism for stabilization and immobilization of E-cadherin". Cavey, M., Rauzi, M., Lenne, P-F. and Lecuit, T. Nature. 2008. 453(7196):751-6
  • "Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis". Rauzi, M., Verant, P., Lecuit, T. and Lenne, PF. Nature Cell Biology 2008 Dec;10(12):1401-10
  • "Spatial control of actin organization at adherens junctions by the synaptotagmin like protein Btsz". Pilot F, Philippe JM, Lemmers C, Lecuit T. Nature. 2006 Epub July 9
  • "Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation". Bertet C, Sulak L, Lecuit T. Nature. 2004 Jun 10;429(6992):667-71
  • "Proximal-distal axis formation in the Drosophila leg". Lecuit T, Cohen SM. Nature. 1997 Jul 10;388(6638):139-45
  • "Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing". Lecuit T, Brook WJ, Ng M, Calleja M, Sun H, Cohen SM. Nature. 1996 May 30;381(6581):387-93

Revues de synthèse

  • "Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis". Lecuit T and Lenne PF. Nature Reviews Molecular Cell Biology. 2007 8(8):633-44
  • "Force generation, transmission and integration during cell and tissue morphogenesis". Lecuit, T., Lenne, PF., and Munro E. Annual Reviews Cell and Developmental Biology. 2011, 27:157-84
  • "Biomechanical regulation of contractility: spatial control and dynamics". Levayer, R. and Lecuit, T. Trends in Cell Biology, 2012 Feb;22(2):61-81
  • "Mechanics of epithelial tissue homeostasis and morphogenesis". Guillot C, Lecuit T. Science. 2013, Jun 7;340(6137):1185-9
  • "Mechanical Forces and Growth in animal tissues". LeGoff L. and Lecuit T. Cold Spring Harb Perspect Biol. 2015 Aug 10. pii: a019232
  • "E-cadherin junctions as active mechanical integrators in tissue dynamics". Lecuit T. and Yap AS. Nature Cell Biology 2015 Apr 30;17(5):533-539. doi: 10.1038/ncb3136