from Tuesday 10 June to Wednesday 11 June 2025 See also: Edith Heard Detail from the mosaic at Tsipori (Sepphoris), "house of Dionysus", Israel. cc0. Organised by: Pre Edith Heard (Collège de France, Chair of Epigenetics and Cellular Memory) and Pre Claire Rougeulle (Institut Curie) Documents and media Download poster pdf (622.13 KB) Program Symposium 08:55 - 09:00 Introduction Edith Heard, Claire Rougeulle 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 08:55 - 09:00 Symposium 09:00 - 09:30 Not recorded Probing the mechanism of Xist RNA localisation in cis with live-cell super-resolution imaging Neil Brockdorff 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 09:00 - 09:30 Symposium 09:30 - 09:50 Escape from X-inactivation is directly modulated by Xist RNA levels Agnese Loda 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 09:30 - 09:50 Symposium 09:50 - 10:10 X-Chromosome Inactivation Osamu Masui 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 09:50 - 10:10 Symposium 10:10 - 10:30 The impact of sex chromosomes on the mouse preimplantation embryo Daniel Snell 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 10:10 - 10:30 Symposium 11:00 - 11:20 HCFC1, a novel activator of XCI Hegias Mira Bontenbal 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 11:00 - 11:20 Symposium 11:20 - 11:40 Mechanisms of sexual dimorphism in liver physiology and cancer James Cleland 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 11:20 - 11:40 Symposium 11:40 - 12:00 X-Chromosome Inactivation Dounia Djeghloul 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 11:40 - 12:00 Symposium 12:00 - 12:30 Using marsupials to understand the evolution of mammalian X inactivation James Turner 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 12:00 - 12:30 Symposium 14:00 - 14:20 Exploring the Role of XIST in X-Chromosome Regulation During Early Human Development Charbel Alfeghaly 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 14:00 - 14:20 Symposium 14:20 - 15:40 Balancing the X: From Mouse X-Chromosome Upregulation to Human X-Chromosome Inactivation Vincent Pasque 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 14:20 - 15:40 Symposium 15:40 - 16:00 Not recorded X-chromosome dynamics in Cynomolgus monkeys Ikuhiro Okamoto 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 15:40 - 16:00 Symposium 16:30 - 16:50 Exploring X-inactivation’s raison-d'être Rafael Galupa 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 16:30 - 16:50 Symposium 16:30 - 16:50 Canceled Reprogramming the X-chromosome: insights from the germline Maud Borensztein 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 16:30 - 16:50 Symposium 16:50 - 17:10 Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function Elphège Nora 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 16:50 - 17:10 Symposium 17:10 - 17:30 How is X-chromosome inactivation restricted to females? Edda Schultz 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 17:10 - 17:30 Symposium 17:30 - 18:00 Inactive X chromosome erosion in TNT reprogrammed hiSPC Marnie Blewitt 10 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 10 Jun 2025 17:30 - 18:00 Symposium 09:00 - 09:30 Xist RNA and XCI maintenance mechanisms in female B cells Monserrat Anguera 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 09:00 - 09:30 Symposium 09:30 - 09:50 Modulation of X chromosome inactivity and phenotypic consequences Céline Morey 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 09:30 - 09:50 Symposium 09:50 - 10:10 Not recorded Tlr7 bi-allelism defines a functionally distinct B cell subset and drives systemic autoimmunity Jean-Charles Guery 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 09:50 - 10:10 Symposium 10:10 - 10:30 Not recorded Sex bias in immunity: alteration of X-chromosome inactivation of the TLR7 locus and autoimmunity Julie Chaumeil 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 10:10 - 10:30 Symposium 10:30 - 10:50 Not recorded EZHIP is required to maintain H3K27me3-dependant imprinting post fertilization in mice Raphael Margueron 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 10:30 - 10:50 Symposium 10:50 - 11:20 XIST and the Maintenance of XCI: Lessons from XCI Erosion in Human Pluripotent Stem Cells Simão José Teixeira da Rocha 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 10:50 - 11:20 Symposium 11:20 - 11:40 Closing words Edith Heard 11 Jun 2025 X-Chromosome Inactivation Amphithéâtre Maurice Halbwachs, Site Marcelin Berthelot 11 Jun 2025 11:20 - 11:40 See also Edith Heard, chair Epigenetics and Cellular Memory