Probing the mechanism of Xist RNA localisation in cis with live-cell super-resolution imaging

Speaker(s)

Neil Brockdorff

University of Oxford, UK

Events

Introduction

Probing the mechanism of Xist RNA localisation in cis with live-cell super-resolution imaging

Balancing the X: From Mouse X-Chromosome Upregulation to Human X-Chromosome Inactivation

X-Chromosome Inactivation

X-Chromosome Inactivation

Exploring X-inactivation’s raison-d'être

X-Chromosome Inactivation

Inactive X chromosome erosion in TNT reprogrammed hiSPC

Xist RNA and XCI maintenance mechanisms in female B cells

X-Chromosome Inactivation

Tlr7 bi-allelism defines a functionally distinct B cell subset&nb…

X-Chromosome Inactivation

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

X-Chromosome Inactivation

X-Chromosome Inactivation

Probing the mechanism of Xist RNA localisation in cis with live-cell super-resolution imaging

Keynote

Speaker(s)

Neil Brockdorff

Events

Introduction

Probing the mechanism of Xist RNA localisation in cis with live-cell super-resolution imaging

X-Chromosome Inactivation

X-Chromosome Inactivation

The impact of sex chromosomes on the mouse preimplantation embryo

HCFC1, a novel activator of XCI

Mechanisms of sexual dimorphism in liver physiology and cancer

X-Chromosome Inactivation

Using marsupials to understand the evolution of mammalian X inactivation

Exploring the role of XIST during early human development

Balancing the X: From Mouse X-Chromosome Upregulation to Human X-Chromosome Inactivation

X-Chromosome Inactivation

X-Chromosome Inactivation

Exploring X-inactivation’s raison-d'être

X-Chromosome Inactivation

Inactive X chromosome erosion in TNT reprogrammed hiSPC

Xist RNA and XCI maintenance mechanisms in female B cells

X-Chromosome Inactivation

Tlr7 bi-allelism defines a functionally distinct B cell subset&nb…

X-Chromosome Inactivation

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

X-Chromosome Inactivation

X-Chromosome Inactivation

Closing words

See also