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Abstract Pancreatic adenocarcinoma (PDA) is one of the most lethal cancers, primarily due to late diagnosis. PDA is a highly stromal (desmoplastic) and poorly vascularized tumor with a dense extracellular matrix; only ~10% of the cells in the tumor are …

Abstract Protein phosphorylation is not restricted to serine, threonine and tyrosine, but can occur on six other amino acids, including histidine. In this lecture, I will discuss what is known about non-canonical protein phosphorylation, focusing on our …

Abstract In this lecture I will discuss the role of PTMs in increasing proteome complexity, why this is important for organisms with genomes of limited protein-coding capacity, and how the combinatorial use of PTMs on a single protein molecule can …

Abstract Although its name refers back to the ancient site of Olympia, Olympism is a modern invention, and our Olympic games are very different from ancient competitions. After a brief evocation of some of these distinctions, the round table will focus on …

Abstract In the second lecture, we turn to an application of the account of propaganda, ideological words that abstractly encapsulate core values of an ideology as their meaning. The focus will be on pejorative words - racist, sexist, homophobic, …

Lauri Mälksoo has been invited by the Collège de France assembly, at the suggestion of Pr   Samantha Besson. The lecture is in English. Documents and media Download program Abstract In its attempts to justify its war (or 'special military operation') …

Abstract This lecture will provide an introduction to the world of post-translational modifications (PTMs) of proteins. Chemical modifications of protein surfaces serves as a mechanism to increase proteome diversity. More than 400 different PTMs are …

Abstract The first lecture will develop the notion of ideologies as folk scientific theories, the institutionalization of those ideologies, and how propaganda supports the principles and values of ideologies so construed through aesthetic and linguistic …

Abstract In this lecture, I will discuss recent work showing the effects of advancing age on neural stem cells. For example, his group had provided the first description of a diffusion barrier in the endplasmic reticulum (ER) in mammalian cells that …

Jennifer Pitts has been invited by the assembly of the Collège de France, at the suggestion of Pr   Antoine Lilti. Abstract Quobna Ottobah Cugoano's Thoughts and Sentiments on the Evil of Slavery (1787), one of the most radical anti-slavery treatises …